Enfrentamento da hanseníase em tempos de COVID-19: uma experiência exitosa de implantação de um sistema de rastreamento em área endêmica do Nordeste / Coping with leprosy in times of COVID-19: a successful experience of implementing a tracking system in an endemic area in the Northeast / Enfrentando la lepra en tiempos de COVID-19: una experiencia exitosa de implementación de un sistema de rastreo en un área endémica del Nordeste

Introdução: A COVID-19 (coronavirus disease 2019) trouxe inúmeros desafios e sobrecarga ao Sistema Único de Saúde (SUS), gerando dificuldades no enfrentamento das outras enfermidades endêmicas e negligenciadas no território brasileiro, entre elas a hanseníase. Objetivo: Relatar a experiência de enfrentamento da prevalência oculta de hanseníase por uma equipe de atenção primária à saúde do interior do estado de Sergipe durante a pandemia de COVID-19. Métodos: O projeto foi desenvolvido entre os meses de setembro de 2020 e janeiro de 2021 e caracterizou-se pela oferta de exame dermatológico aos indivíduos que buscaram atendimento na unidade de saúde do bairro Cidade Nova, em Estância, Sergipe. Confirmado o diagnóstico de hanseníase, foi introduzido o tratamento com esquema de poliquimioterapia da Organização Mundial da Saúde (PQT-OMS) e os contatos foram examinados, respeitando-se as medidas sanitárias de prevenção à contaminação pela COVID-19. Resultados: No período analisado, foram avaliados 235 indivíduos, sendo feitos seis diagnósticos clínicos de hanseníase (2,5%), entre os quais um em menor de 15 anos de idade. No município, durante todo o ano de 2020, registrou-se o total de nove casos novos de hanseníase. Sem o projeto, o coeficiente de detecção de casos novos de hanseníase no município seria de 4,3/100 mil habitantes e, com o projeto, esse coeficiente foi três vezes superior (12,9/100 mil habitantes). Conclusão: A oferta de exame dermatoneurológico durante consultas médicas de rotina em áreas vulneráveis permitiu evidenciar a prevalência oculta de hanseníase no bairro Cidade Nova, Estância. Além disso, ações dessa natureza permitem o diagnóstico precoce, evitando-se a evolução para incapacidades físicas.

Introduction: COVID-19 (coronavirus disease 2019) has brought numerous challenges and burdens on the Unified Health System (SUS, acronym in Portuguese), creating difficulties for the facing of other endemic diseases in the Brazilian territory, such as leprosy. Objective: To report an experience of coping with the hidden prevalence of leprosy by a primary health care team in the countryside of the state of Sergipe during the COVID-19 pandemic. Methods: The project was developed from September 2020 to January 2021 and was characterized for offering a dermatological examination to individuals seeking care at the health unit in the Cidade Nova neighborhood, Estância, Sergipe. For confirmed cases, treatment was instituted and household contacts were examined, respecting the measures to prevent contamination by COVID-19. Results: In the analyzed period, 235 individuals were evaluated, with six diagnoses of leprosy (2.5%), one under the age of 15. In 2020, the municipality registered nine total cases. Without the project, the detection rate of new leprosy cases in the municipality would have been 4.3/100,000 inhabitants and, with the project, this coefficient was three times higher (12.9/100,000 inhabitants). Conclusion: The offer of dermato-neurological exams during routine medical appointments made it possible to show the hidden prevalence of leprosy in the neighborhood of Cidade Nova, Estância. In addition, actions of this nature allow early diagnosis, preventing the occurrence of physical disabilities.

Introducción: La COVID-19 (enfermedad por coronavirus 2019) trajo numerosos desafíos y cargas al Sistema Único de Salud (SUS), creando dificultades para enfrentar otras enfermedades endémicas en el territorio brasileño, como la lepra. Objetivo: Informar una experiencia de afrontamiento de la prevalencia oculta de lepra por parte de un equipo de atención primaria en el interior del estado de Sergipe durante la pandemia de COVID-19. Métodos: El proyecto se desarrolló desde septiembre de 2020 hasta enero de 2021 y se caracterizó por ofrecer un examen dermatológico a las personas que buscaban atención en la unidad de salud del barrio Cidade Nova, en Estância, Sergipe. En caso de confirmarse los casos, se instituyó el tratamiento y se examinaron los contactos domiciliarios, respetando las medidas para prevenir la contaminación por COVID-19. Resultados: En el período analizado se evaluaron 235 individuos, con 06 diagnósticos de lepra (2,5%), uno menor de 15 años. En 2020, el municipio registró nueve casos en total. Sin el proyecto, la tasa de detección de nuevos casos de lepra en el municipio sería de 4,3/100 mil habitantes y, con el proyecto, este coeficiente era tres veces mayor (12,9/100 mil habitantes). Conclusión: La oferta de exámenes dermatoneurológicos durante las consultas médicas de rutina permitió mostrar la prevalencia oculta de la lepra en el barrio Cidade Nova, Estância. Además, acciones de esta naturaleza permiten un diagnóstico precoz, evitando la aparición de discapacidades físicas.

The challenges of the family health strategy in the incidence of congenital syphilis in Pernambuco, Brazil, between 2009 to 2018

INTRODUCTION: Syphilis is a health problem and an issue for maternal and child health. OBJECTIVE: To analyze the incidence of congenital syphilis (CS) and its relationship with the Family Health Strategy (FHS) in the state of Pernambuco, between 2009-2018. METHODS: Observational analytical retrospective study with secondary data provided by the Brazilian National Notifiable Diseases System of the Ministry of Health on syphilis infection during pregnancy, congenital syphilis, and FHS coverage information, made available on the e-Gestor AB platform, between 2009-2018. Microsoft Office Excel, JASP 0.14.1.0 and Statistical Package for the Social Sciences 25 programs, and Shapiro-Wilk test, Spearman, and Chi-Squared test were used for the organization and analysis of sociodemographic and clinical variables. RESULTS: 11,519 cases of CS were reported in Pernambuco between 2009-2018, with a 12% increase in the FHS coverage rate in the state and 376% growth in the detection rate of CS per thousand live births in the analyzed period. Of the maternal sociodemographic characteristics, there was a higher occurrence of infection in women aged 20 to 29 years (52.76%), black (77.53), and incomplete elementary school or no education (49.56%). In 90.29% of the cases, recent congenital syphilis was identified as the final diagnosis. The analysis also revealed that the greater the FHS coverage in the state, the greater the amount of inadequately performed treatments. CONCLUSION: The analysis of CS cases related to the FHS point to weaknesses in the control and proper treatment of the disease, especially in Black women with low education.

Análise dos níveis de escolaridade nos casos de sífilis na gestação e sífilis congênita, no Brasil, 2010-2019

Objetivo: Analisar a relação da escolaridade em casos de sífilis na gestação e congênita no Brasil. Métodos: Estudo observacional analítico retrospectivo, utilizando dados secundários do Sistema de Informação de Agravos de Notificação, coletados entre os meses de março e abril de 2021, referente ao período de 2010-2019, tabulados em planilhas do programa Microsoft Excel 2016. No tratamento estatístico, utilizou-se o software Join Point, analisando as tendências em Variações percentuais anuais (Annual Percentage Change) e em Variação percentual anual média (Average Annual Percentage Change). Resultados: No período analisado, as tendências de sífilis na gestação, em mulheres com escolaridade ? 8 anos, apresentou em âmbito nacional e regiões Norte e Nordeste, comportamento significativamente crescentes a partir do Fundamental completo. As regiões Centro-Oeste, Sudeste e Sul apresentaram tendência significativamente crescente nas categorias de escolaridade Médio incompleto e completo, Superior incompleto e completo. Quanto à análise acerca sífilis congênita, há tendências significativamente crescentes nas mães com de 8 anos ou mais de estudo formal no Brasil e nas regiões Nordeste, Centro-oeste, Sudeste e Sul. Acerca da sífilis congênita na região Norte análise estatística aponta às tendências crescentes das categorias de escolaridade Fundamental completo, Médio incompleto e completo, enquanto as categorias Superior incompleto e completo apresentam tendências estacionárias. Conclusões: Tradicionalmente, os casos de sífilis na gestação e sífilis congênita estão associados a baixa escolaridade. Entretanto, o aumento médio da escolaridade da população brasileira e a incidência elevadas dos casos, apontam para a necessidade a reorganização das estratégias de prevenção e controle dessa IST.

Epidemiological and clinical profile and trend analysis of hospitalizations for fall-related injuries among older adults, Alagoas (Brazil), 2008­2019 / Perfil epidemiológico e clínico e tendência temporal de internações por quedas em idosos, Alagoas (Brasil), 2008­2019

Objective: To analyze the epidemiological and clinical profile and the time trend of hospitalizations for fall-related injuries among older people (aged 60 years or older) in Alagoas between 2008 and 2019. Methods: This is a time series study with data collected from the Hospital Information System of the Unified National Health System (SIHSUS) referring to hospitalizations for fallrelated injuries among older adults in Alagoas (Brazil) between 2008 and 2019. Hospitalization and lethality rates, average annual percent change (AAPC), and annual percent change (APC) were calculated; time trends were analyzed using a Joinpoint Regression Model according to sex, skin color, age range, and causes. A 95% confidence interval (95%CI) was adopted. A p-value<0.01 was adopted for defining statistical significance. Results: In Alagoas, 14 817 cases of hospitalizations due to fall-related injuries were reported among older people in the analyzed period. The highest incidence rate was observed in 2016 (48.39/10 000 inhabitants). There were 517 deaths, and the mean lethality rate was 3.4%. A higher proportion of cases was seen in men (66.36%; n=9832), those aged 80 years or older(34.59%; n=5125), and with Brown skin (54.70%; n=8106). The incidence coefficient varied, showing an upward trend with time (APC: 4.1; 95%CI 0.2­8.2; p<0.01). Conclusion: The study showed a higher incidence in individuals aged 80 years or older, men, and found an upward trend in hospitalizations. We suggest the'

Objetivo: Analisar o perfil epidemiológico e clínico e a tendência temporal das internações por quedas em idosos de 60 anos ou mais, ocorridas em Alagoas, no período de 2008­2019. Metodologia: Realizou-se um estudo de séries temporais com dados coletados no Sistema de Informações Hospitalares do Sistema Único de Saúde, referentes a internações por quedas em idosos de 60 anos ou mais em Alagoas (Brasil), entre 2008 e 2019. Foram calculadas as taxas de incidência de internação e letalidade, a variação percentual anual média (AAPC) e a variação anual percentual (APC). A tendência foi analisada pelo modelo de regressão por pontos de inflexão (joinpoint regression model) segundo sexo, cor, faixa etária e categoria de causas. Adotou-se intervalo de confiança de 95% (IC95%) e, para análise do nível de significância estatística, valor de p < 0,01. Resultados: Foram notificados 14.817 casos de internações por quedas em idosos de 60 anos ou mais no período analisado, em Alagoas. A maior taxa de incidência ocorreu em 2016 (48,39/10 mil habitantes). Ocorreram 517 óbitos, e a taxa média de letalidade foi de 3,4%. Verificou-se maior proporção de casos no sexo masculino (66,36%; n = 9.832), na faixa etária de 80 anos (34,59%; n = 5.125) e na cor parda (54,70%; n = 8.106). Houve variação do coeficiente de incidência, o qual apresentou comportamento temporal crescente (APC: 4,1; IC95% de 0,2 a 8,2; p < 0,01). Conclusão: O estudo mostrou maior incidência na faixa etária de 80 anos ou mais no período analisado, maior frequência no sexo masculino e tendência crescente de internações. Sugere-se otimizar a assistência hospitalar e incentivar programas de prevenção de quedas em idosos.

Trend analysis of clinical aspects of congenital syphilis in Brazil, 2009-2018.

INTRODUCTION: Congenital syphilis is caused by the vertical transmission of bacteria, Treponema pallidum, from nontreated or inappropriately treated pregnant to the fetus. OBJECTIVE: To evaluate the clinical aspects of Congenital syphilis in Brazil, between 2009-2018. METHOD: It is an analytical cross-sectional study whose data were collected from the Department of Chronical Conditions and Sexually Transmitted Infections of Brazilian Health Ministry. Clinical variables were analyzed using the software Joinpoint Regression, which makes a segmented linear regression. RESULTS: In the study period, 156,969 cases of Congenital syphilis and 1642 deaths by this disease were reported. The trend analysis indicates growing in diagnosis of maternal syphilis during prenatal care, appropriate treatment of pregnant, realization of prenatal care, maternal partner treatment, diagnosis of syphilis in children under seven days, and diagnosis of recent syphilis. CONCLUSIONS: Although the trend analysis presents relative improvement in Congenital syphilis panorama in Brazil, the disease still related to high numbers of evitable perinatal morbidity and mortality. Therefore, the prenatal assistance with quality is fundamental to have a possible change in this field in the country.

Perfil epidemiológico e tendência temporal da mortalidade por suicício em adolescentes / Epidemiological profile and temporal trend of suicide mortality in adolescents

OBJETIVO: Descrever o perfil epidemiológico e analisar a tendência temporal da mortalidade por suicídio entre adolescentes (10-19 anos) do Nordeste brasileiro, no período de 2001 a 2015. MÉTODOS: Trata- -se de estudo observacional, que teve como cenário a região Nordeste do Brasil. O período de estudo foi de 2001 a 2015. Consideraram-se as mortes por lesão autoprovocada intencionalmente (X60 a X84), intoxicação exógena de intenção indeterminada (Y10 a Y19) e sequela de lesões autoprovocadas intencionalmente (Y87.0), de acordo com a 10ª Revisão da Classificação Internacional de Doenças (CID-10), de adolescentes de 10 a 19 anos. As variáveis analisadas foram: sexo, faixa etária, raça/cor, CID específico, estado de residência e taxa de mortalidade por suicídio/100.000 habitantes. RESULTADOS: Foram registrados 3.194 óbitos em decorrência de suicídio na faixa etária estudada, com predomínio do sexo masculino (62,1%; n = 1.984), faixa etária de 15 a 19 anos (84,8%; n = 2.707), raça/cor parda (65,4%; n = 2.090); entre quatro e sete anos de escolaridade (31,7%; n = 1.011) e no CID X70 (47,8%; n = 1.528). A tendência temporal de mortalidade foi crescente de 2001 a 2015 (APC: 2,4%; p < 0,01), com maiores taxas no sexo masculino. Observou-se tendência crescente da taxa de suicídios, no sexo masculino, em todo o período (AAPC: 2,9%; p < 0,01). No sexo feminino, identificou-se tendência decrescente a partir de 2004 (APC: -2,2%; p < 0,01). CONCLUSÃO: O perfil epidemiológico foi caracterizado pelo sexo masculino, faixa etária de 15-19 anos, cor/raça parda e escolaridade média. A tendência apresentou padrão de crescimento no sexo masculino e declínio no feminino. Recomenda-se que políticas públicas sejam voltadas para a população adolescente.

OBJECTIVE: To describe the epidemiological profile and analyze the time trend of suicide mortality among adolescents (10-19 years old) from the Brazilian Northeast, from 2001 to 2015. METHODS: This is an observational study, which took place in the Northeast region, Brazil. The study period was from 2001 to 2015. Deaths from intentional self-harm (X60 to X84). exogenous poisoning of undetermined intent (Y10 to Y19) and intentional self-harm (Y87.0) were considered, according to the 10th Review of the International Classification of Diseases (ICD-10), for adolescents aged 10 to 19 years. The variables analyzed were: sex, age group, race / color, specific ICD, state of residence and suicide mortality rate/100,000 inhabitants. RESULTS: There were 3,194 deaths due to suicide in the age group studied, with a male predominance (62.1%; n = 1,984), age group 15 to 19 years (84.8%; n = 2,707), race/brown color (65.4%; n = 2,090); between 4 and 7 years of schooling (31.7%; n = 1,011) and at CID X70 (47.8%; n = 1,528). The time trend of mortality was increasing from 2001 to 2015 (APC: 2.4%; p < 0.01), with higher rates in males. There was an increasing trend in the suicide rate, among men, throughout the period (AAPC: 2.9%; p < 0.01). In women, a decreasing trend was identified as of 2004 (APC: -2.2%; p < 0.01). CONCLUSION: The epidemiological profile was characterized by male gender, age group 15-19 years, color/brown race and average schooling. The trend showed a growth pattern in males and a decline in females. It is recommended that public policies are aimed at the adolescent population.

Trend analysis of clinical aspects of congenital syphilis in Brazil, 2009-2018

SUMMARY INTRODUCTION: Congenital syphilis is caused by the vertical transmission of bacteria, Treponema pallidum, from nontreated or inappropriately treated pregnant to the fetus. OBJECTIVE: To evaluate the clinical aspects of Congenital syphilis in Brazil, between 2009-2018. METHOD: It is an analytical cross-sectional study whose data were collected from the Department of Chronical Conditions and Sexually Transmitted Infections of Brazilian Health Ministry. Clinical variables were analyzed using the software Joinpoint Regression, which makes a segmented linear regression. RESULTS: In the study period, 156,969 cases of Congenital syphilis and 1642 deaths by this disease were reported. The trend analysis indicates growing in diagnosis of maternal syphilis during prenatal care, appropriate treatment of pregnant, realization of prenatal care, maternal partner treatment, diagnosis of syphilis in children under seven days, and diagnosis of recent syphilis. CONCLUSIONS: Although the trend analysis presents relative improvement in Congenital syphilis panorama in Brazil, the disease still related to high numbers of evitable perinatal morbidity and mortality. Therefore, the prenatal assistance with quality is fundamental to have a possible change in this field in the country.

Airports, highways and COVID-19: An analysis of spatial dynamics in Brazil.

INTRODUCTION: The high transmissibility and infectivity of the new coronavirus, the high proportion of asymptomatic transmitters and the rapid and continuous spatial displacement of people, by the different mechanisms of locomotion, are elements that can contribute to the dissemination of COVID-19. This study aims to describe the geographical dispersion of COVID-19 in the state of Bahia and the importance of major airports and highways in the dynamics of disease transmission. METHODS: This is an ecological study involving all cases of COVID-19 registered in the state of Bahia between March 6, date of the first registered case and May 16, 2020. After collection, an exploratory spatial analysis was performed, considering the cases accumulated on the last day of each epidemiological week. RESULTS: The first cases of COVID-19 were concentrated in areas served by three important airport complexes in the state, located in Salvador, Ilhéus and Porto Seguro. From week 16-20, there was a more intense expansion of COVID-19 to the interior of the state. A global spatial autocorrelation was observed (I Moran 0.2323; p = 0.01), with the influence of distance: positive correlation at distances less than 205.8 km (I Moran 0.040; p = 0.01) and greater than 800 km (I Moran 0.080; p = 0.01). CONCLUSIONS: Based on the spatial dispersion pattern of COVID-19 in the state of Bahia, airports and highways that cross the state were responsible for the interiorization of the disease.

[Spatial and temporal patterns of mortality among motorcyclists in a State of the Brazilian Northeast in the 21st century]. / Padrões espaciais e temporais da mortalidade de motociclistas em estado do nordeste brasileiro no século XXI.

The scope of this work was to analyze the trend and distribution of mortality among motorcyclists in traffic accidents in the State of Alagoas. It involved an ecological study relating to all deaths resulting from motorcycle accidents in the state in the period from 2001 to 2015. Mortality data were obtained from the Mortality Information System (MIS). Mortality rates were calculated and stratified by gender. The joinpoint regression model was used for trend analysis and the Annual Percentage Variation (APV) was calculated with a significance rate of 5%. For the spatial analysis, local empirical Bayesian modeling and Moran statistics and spatial scanning statistics were applied. There were 1,458 deaths of motorcyclists in the period studied, 91.3% of which were men. Three temporal behaviors were observed in this population group: growth (2001-2005), stationary pattern (2005-2013) and decline from 2013 onwards. The highest rates were observed in the 'agreste' and 'sertão' regions of the state of Alagoas. Five spatial clusters were revealed with relation to general and male mortality, all located in the 'agreste' and 'sertão' hinterlands of Alagoas. The modeling showed a reduction of mortality from 2013 onwards and the spatial analysis revealed that the problem is more acute in the interior of the state.

Este trabalho objetivou analisar a tendência e a distribuição espacial da mortalidade de motociclistas em acidentes de transporte no estado de Alagoas. Trata-se de um estudo ecológico referente a todos os óbitos decorrentes de acidentes motociclísticos no estado no período 2001-2015. Os dados de mortalidade foram obtidos do Sistema de Informações sobre Mortalidade (SIM). As taxas de mortalidade foram calculadas e estratificadas por sexo. Para a análise de tendência, foi empregado o modelo de regressão por pontos de inflexão. Calculou-se a Variação Percentual Anual (VPA). Significância de 5%. Para a análise espacial, aplicou-se modelagem bayesiana empírica local, estatística de Moran e estatística de varredura espacial. Foram registrados 1.458 óbitos de motociclistas no período estudado, sendo 91,3% homens. Três comportamentos temporais foram observados nessa população: crescimento (2001-2005), padrão estacionário (2005-2013) e declínio a partir de 2013. As maiores taxas foram observadas no agreste e sertão. Cinco aglomerados espaciais foram evidenciados no que se refere à mortalidade geral e masculina, todos situados no agreste e sertão alagoanos. A modelagem mostrou redução da mortalidade a partir de 2013 e a análise espacial evidenciou que o problema é mais grave no interior do estado.

COVID-19 in Brazil: spatial risk, social vulnerability, human development, clinical manifestations and predictors of mortality - a retrospective study with data from 59 695 individuals.

Brazil ranks second in the number of confirmed cases of COVID-19 worldwide. In spite of this, coping measures differ throughout the national territory, as does the disease's impact on the population. This cross-sectional observational study, with 59 695 cases of COVID-19 registered in the state of Alagoas between March and August 2020, analysed clinical-epidemiological variables, incidence rate, mortality rate, case fatality rate (CFR) and the social indicators municipal human development index (MHDI) and social vulnerability index (SVI). Moran statistics and regression models were applied. Logistic regression analysis was applied to determine the predictors of death. The incidence rate was 1788.7/100 000 inhabitants; mortality rate was 48.0/100 000 and CFR was 2.7%. The highest incidence rates were observed in municipalities with better human development (overall MHDI (I = 0.1668; p = 0.002), education MHDI (I = 0.1649; p = 0.002) and income MHDI (I = 0.1880; p = 0.005)) and higher social vulnerability (overall SVI (I = 0.0599; p = 0.033)). CFR was associated with higher social vulnerability (SVI human capital (I = 0.0858; p = 0.004) and SVI urban infrastructure (I = 0.0985; p = 0.040)). Of the analysed cases, 55.4% were female; 2/3 were Black or Brown and the median age was 41 years. Among deaths, most were male (919; 57.4%) and elderly (1171; 73.1%). The predictors of death were male sex, advanced age and the presence of comorbidities. In Alagoas, Brazil, the disease has undergone a process of interiorisation and caused more deaths in poorer municipalities. The presence of comorbidities and advanced age were predictors of death.

Padrões espaciais e temporais da mortalidade de motociclistas em estado do nordeste brasileiro no século XXI / Spatial and temporal patterns of mortality among motorcyclists in a State of the Brazilian Northeast in the 21st century

Resumo Este trabalho objetivou analisar a tendência e a distribuição espacial da mortalidade de motociclistas em acidentes de transporte no estado de Alagoas. Trata-se de um estudo ecológico referente a todos os óbitos decorrentes de acidentes motociclísticos no estado no período 2001-2015. Os dados de mortalidade foram obtidos do Sistema de Informações sobre Mortalidade (SIM). As taxas de mortalidade foram calculadas e estratificadas por sexo. Para a análise de tendência, foi empregado o modelo de regressão por pontos de inflexão. Calculou-se a Variação Percentual Anual (VPA). Significância de 5%. Para a análise espacial, aplicou-se modelagem bayesiana empírica local, estatística de Moran e estatística de varredura espacial. Foram registrados 1.458 óbitos de motociclistas no período estudado, sendo 91,3% homens. Três comportamentos temporais foram observados nessa população: crescimento (2001-2005), padrão estacionário (2005-2013) e declínio a partir de 2013. As maiores taxas foram observadas no agreste e sertão. Cinco aglomerados espaciais foram evidenciados no que se refere à mortalidade geral e masculina, todos situados no agreste e sertão alagoanos. A modelagem mostrou redução da mortalidade a partir de 2013 e a análise espacial evidenciou que o problema é mais grave no interior do estado.

Abstract The scope of this work was to analyze the trend and distribution of mortality among motorcyclists in traffic accidents in the State of Alagoas. It involved an ecological study relating to all deaths resulting from motorcycle accidents in the state in the period from 2001 to 2015. Mortality data were obtained from the Mortality Information System (MIS). Mortality rates were calculated and stratified by gender. The joinpoint regression model was used for trend analysis and the Annual Percentage Variation (APV) was calculated with a significance rate of 5%. For the spatial analysis, local empirical Bayesian modeling and Moran statistics and spatial scanning statistics were applied. There were 1,458 deaths of motorcyclists in the period studied, 91.3% of which were men. Three temporal behaviors were observed in this population group: growth (2001-2005), stationary pattern (2005-2013) and decline from 2013 onwards. The highest rates were observed in the 'agreste' and 'sertão' regions of the state of Alagoas. Five spatial clusters were revealed with relation to general and male mortality, all located in the 'agreste' and 'sertão' hinterlands of Alagoas. The modeling showed a reduction of mortality from 2013 onwards and the spatial analysis revealed that the problem is more acute in the interior of the state.

Novo século, velho problema: tendência da mortalidade infantil e seus componentes no Nordeste brasileiro / New century, old problems: infant mortality trend and its components in the northeast region of Brazil

Resumo Introdução A mortalidade infantil ainda representa um desafio para os países em desenvolvimento. Objetivo Analisar a tendência da mortalidade infantil e seus componentes nos estados do Nordeste brasileiro entre 2001 e 2015. Método Estudo ecológico envolvendo quatro indicadores de mortalidade infantil: geral, neonatal precoce, neonatal tardia e pós-neonatal. Foi aplicado o modelo de regressão por pontos de inflexão (joinpoint regression). A tendência foi classificada em crescente, decrescente ou estacionária. Calculou-se o Percentual de Variação Anual (APC, Annual Percent Change), considerando Intervalo de Confiança de 95%. Resultados Foi observada tendência decrescente da mortalidade infantil geral no Nordeste (-3,9%) e em todos os estados, sendo Pernambuco com maior redução (-5,2%). Na mortalidade neonatal precoce, somente o Maranhão apresentou tendência estacionária (-0,2%). Na mortalidade neonatal tardia, Maranhão, Piauí, Paraíba e Sergipe apresentaram padrão estacionário. A mortalidade pós-neonatal foi a que apresentou maior redução, tendo destaque Alagoas (-8,6%) e Pernambuco (-7,6%). No Nordeste, esse componente apresentou variação anual de -6,1%. A partir do final da primeira década, a mortalidade pós-neonatal apresentou padrão estacionário no Nordeste, destacando-se Maranhão, Ceará, Rio Grande do Norte e Sergipe. Conclusão Embora tenha sido verificada redução da mortalidade infantil no Nordeste do Brasil, o comportamento estacionário em alguns estados configura motivo de preocupação, tendo em vista que os valores ainda são muito elevados quando comparados aos de locais desenvolvidos.

Abstract Background Infant mortality still represents a challenge for developing countries. Objective To assess the infant mortality trend and its components in the Brazilian Northeast states between 2001 and 2015. Method Ecological study consisting of four indicators of infant mortality were analyzed as following: general, early neonatal, late neonatal and post-neonatal mortalities. A regression analysis was applied to fit the inflection point (joinpoint regression). The trends were classified as increasing, decreasing or stationary. The Annual Percent Change (APC) was calculated considering a 95% confidence interval. Results Decreasing trend of overall infant mortality in the Northeast region (-3.9%) could be measured; the state of Pernambuco showed the greatest reduction (-5.2%). Regarding the early neonatal mortality, only the state of Maranhão showed stationary trends (-0.2%). With respect to the late neonatal mortality, the states of Maranhão, Piauí, Paraíba and Sergipe showed stationary pattern. The post-neonatal mortality presented the greatest reduction, being highlighted the values of this significant reduction in the states of Alagoas (-8.6) and Pernambuco (-7.6). Considering the entire region, this component showed an APC of -6.1%. At the end of the first decade, post-neonatal mortality showed a stationary pattern over the Northeast region, with the highest values in the states of Maranhão, Ceará, Rio Grande do Norte and Sergipe. Conclusion Although it has been a reduction in infant mortality in Northeastern Brazil, the stationary pattern in some states produced reasons for concern, considering that rates are still very elevated when compared to developed areas.

Pandemia: vivências de médicos da atenção primária à saúde e de mestrandos em Saúde da Família / Pandemic: experiences of primary health care doctors and master's degree students in family health

Resumo: Introdução: A Covid-19 trouxe uma série de desafios para o Sistema Único de Saúde. Na atenção primária à saúde (APS), tais desafios se somam aos já existentes. Objetivo: Este estudo teve como objetivo analisar a vivência de enfrentamento da pandemia de Covid-19 entre médicos do Programa Mais Médicos Brasil, mestrandos em Saúde da Família e atuantes na APS. Método: Trata-se de estudo qualitativo envolvendo oito médicos da APS de Alagoas que cursam o Mestrado Profissional em Saúde da Família (PROFSAÚDE). Foram elaboradas cinco questões, cujas respostas foram analisadas com base na teoria de Análise de Conteúdo. Resultado: Observaram-se três categorias e quatro subcategorias: categoria 1 - "Processo de estudo e de trabalho" (subcategoria 1.1 - "Características do PROFSAÚDE" - e subcategoria 1.2 - "Estratégias pessoais desenvolvidas"), categoria 2 - "Desafios no gerenciamento da vida" (subcategoria 2.1 - "Mudanças no cotidiano" - e subcategoria 2.2 - "Impacto nas emoções") e categoria 3 - "Crescimento pessoal e profissional". Conclusão: Em tempos de pandemia, os profissionais médicos vivenciam situações complexas e dinâmicas em razão de um duplo e acumulativo processo - o trabalho na APS e a condição de mestrando. Apesar de todas as dificuldades enfrentadas, o mestrado possibilitou o aprimoramento das habilidades em lidar com situações críticas.

Abstract: Introduction: COVID-19 has brought numerous challenges for the Health System in Brazil. In Primary Health Care, these challenges add to those that already exist. Objective: To analyze the experience of facing the COVID-19 pandemic among doctors of the Mais Médicos Brasil Program and master's degree students in Family Health and those working in Primary Health Care. Methods: Qualitative study involving eight doctors from Primary Health Care in Alagoas who are also studying the professional master's degree in Family Health (PROFSAÚDE). Five questions were developed, the answers to which were analyzed based on Content Analysis theory. Results: Three categories and four subcategories were observed: Category 1 - Study and work process (Subcategory 1.1- Characteristics of PROFSAÚDE; Subcategory 1.2 - Personal strategies developed); Category 2 - Challenges in Life Management (Subcategory 2.1 - Changes in daily life; Subcategory 2.2 - Impact on emotions) and Category 3 - Personal and Professional Growth. Conclusion: During the pandemic, medical professionals experience complex and dynamic situations due to a dual and cumulative process - working in PHC and studying for their master's degree. Despite all the difficulties faced, the master's degree allowed them to improve skills in dealing with critical situations.

Mortality of motorcyclists due to traffic injuries in Brasil: a population-based study in Brazilian capitals.

OBJECTIVE: To analyze the mortality trend of young men who were victims of traffic injuries involving motorcycles in all Brazilian capitals from 2001 to 2015. METHODS: A time-series study on all deaths of men aged 20-39 years old due to traffic injuries involving motorcycles in all 27 Brazilian capitals. We used the joinpoint regression model for temporal analysis and calculated the Annual Percent Change (APC) and Average Annual Percent Change (AAPC) to verify the mortality trends. RESULTS: A total of 12,058 deaths of young men were recorded in the Brazilian capitals during the period studied. The highest mortality rates were observed in Boa Vista/Roraima (34.0/100,000 population) and Palmas/Tocantins (29.80/100,000). Twelve of the 27 capitals showed an increasing trend in mortality, with the highest percentage increase being observed in Salvador (APC: 29.0%) and São Paulo (APC: 13.1%). None of the capitals showed a decline in the trend of mortality. CONCLUSIONS: Overall, the mortality of young men from traffic injuries involving motorcycles shows an increasing trend in 12 of the 27 capitals, which represents a public health problem that requires the implementation of more effective public policies.

Mortality of motorcyclists due to traffic injuries in Brasil: a population-based study in Brazilian capitals

SUMMARY OBJECTIVE: To analyze the mortality trend of young men who were victims of traffic injuries involving motorcycles in all Brazilian capitals from 2001 to 2015. METHODS: A time-series study on all deaths of men aged 20-39 years old due to traffic injuries involving motorcycles in all 27 Brazilian capitals. We used the joinpoint regression model for temporal analysis and calculated the Annual Percent Change (APC) and Average Annual Percent Change (AAPC) to verify the mortality trends. RESULTS: A total of 12,058 deaths of young men were recorded in the Brazilian capitals during the period studied. The highest mortality rates were observed in Boa Vista/Roraima (34.0/100,000 population) and Palmas/Tocantins (29.80/100,000). Twelve of the 27 capitals showed an increasing trend in mortality, with the highest percentage increase being observed in Salvador (APC: 29.0%) and São Paulo (APC: 13.1%). None of the capitals showed a decline in the trend of mortality. CONCLUSIONS: Overall, the mortality of young men from traffic injuries involving motorcycles shows an increasing trend in 12 of the 27 capitals, which represents a public health problem that requires the implementation of more effective public policies.

RESUMO OBJETIVO: Analisar a tendência temporal da mortalidade de homens jovens vítimas de acidente de trânsito envolvendo motocicletas em todas as capitais brasileiras de 2001 a 2015. MÉTODOS: Estudo de séries temporais incluindo as mortes de homens de 20 a 39 anos por lesões no trânsito envolvendo motocicletas nas 27 capitais brasileiras. Para a análise, foi utilizado o modelo de regressão do ponto de inflexão e calculada a Variação Percentual Anual (APC) e a Variação Percentual Anual Média (AAPC). RESULTADOS: Foram registradas 12.058 mortes de homens jovens nas capitais brasileiras durante o período estudado. As maiores taxas de mortalidade foram observadas em Boa Vista/Roraima (34,0/100.000 habitantes) e Palmas/Tocantins (29,80/100.000). Doze capitais apresentaram tendência crescente de mortalidade, sendo o maior aumento percentual em Salvador (APC: 29,0%) e São Paulo (APC: 13,1%). Nenhuma das capitais mostrou declínio nas taxas. CONCLUSÕES: A mortalidade de jovens por lesões no trânsito envolvendo motocicletas tem mostrado uma tendência crescente em 12 capitais, o que representa um problema de saúde pública que requer a implementação de políticas públicas mais eficazes.

Human development, social vulnerability and COVID-19 in Brazil: a study of the social determinants of health.

BACKGROUND: Coronavirus disease 2019 (COVID-19) was confirmed in Brazil in February 2020. Since then, the disease has spread throughout the country, reaching the poorest areas. This study analyzes the relationship between COVID-19 and the population's living conditions. We aimed to identify social determinants related to the incidence, mortality, and case fatality rate of COVID-19 in Brazil, in 2020. METHODS: This is an ecological study evaluating the relationship between COVID-19 incidence, mortality, and case fatality rates and 49 social indicators of human development and social vulnerability. For the analysis, bivariate spatial correlation and multivariate and spatial regression models (spatial lag model and spatial error models) were used, considering a 95% confidence interval and a significance level of 5%. RESULTS: A total of 44.8% of municipalities registered confirmed cases of COVID-19 and 14.7% had deaths. We observed that 56.2% of municipalities with confirmed cases had very low human development (COVID-19 incidence rate: 59.00/100 000; mortality rate: 36.75/1 000 000), and 52.8% had very high vulnerability (COVID-19 incidence rate: 41.68/100 000; mortality rate: 27.46/1 000 000). The regression model showed 17 indicators associated with transmission of COVID-19 in Brazil. CONCLUSIONS: Although COVID-19 first arrived in the most developed and least vulnerable municipalities in Brazil, it has already reached locations that are farther from large urban centers, whose populations are exposed to a context of intense social vulnerability. Based on these findings, it is necessary to adopt measures that take local social aspects into account in order to contain the pandemic.